An alternative to LASIK eye surgery – electromechanical remodelling

Summary

The electromechanical reshaping technique successfully flattened this rabbit cornea, shown in a cross section, from its original shape (white line) to a corrected one (yellow line). Credit: Daniel Kim and Mimi Chen Millions of Americans have altered vision, ranging from blurriness to blindness. But not everyone wants to wear prescription glasses or contact lenses. Accordingly, hundreds of thousands of people undergo corrective eye surgery each year, including LASIK—a laser-assisted surgery that reshapes the cornea and corrects vision. The procedure can result in negative side effects, prompting researchers to take the laser out of LASIK by remodeling the cornea, rather than cutting it, in initial animal tissue tests. Michael Hill, a professor of chemistry at Occidental College, presented his team's results at the fall meeting of the American Chemical Society (ACS Fall 2025) held Aug. 17–21. Human corneas are dome-shaped, clear structures that sit at the front of the eye, bending light from surroundings and focusing it onto the retina, where it's sent to the brain and interpreted as an image. But if the cornea is misshapen, it doesn't focus light properly, resulting in a blurry image. With LASIK, specialized lasers reshape the cornea by removing precise sections of the tissue. This common procedure is considered safe, but it has some limitations and risks, and cutting the cornea compromises the structural integrity of the eye. Hill explains that "LASIK is just a fancy way of doing traditional surgery. It's still carving tissue—it's just carving with a laser." But what if the cornea could be reshaped without the need for any incisions? This is what Hill and collaborator Brian Wong are exploring through a process known as electromechanical reshaping (EMR). "The whole effect was discovered by accident," explains Wong, a professor and surgeon at the University of California, Irvine. "I was looking at living tissues as moldable materials and discovered this whole process ...