Human Ontology Project A comprehensive computational model of human biology using Rust's type system to enable simulation, analysis, and diagnosis of biological systems. ๐ฏ Vision Create an accurate, type-safe model of the human body that can: Simulate biological processes at multiple scales biological processes at multiple scales Analyze individual variations (genetics, ancestry, conditions) individual variations (genetics, ancestry, conditions) Diagnose health conditions and predict outcomes health conditions and predict outcomes Enable personalized medicine applications ๐ Current Status โ 114 Rust source files (+9 genetic modules) โ 483 passing tests (100% coverage) โ 13 complete body systems โ Comprehensive genetic disease markers โ Full diagnostic assessment engine โ Advanced pharmacogenomic profiling โ Athletic performance genetics โญ Key Features ๐งฌ Advanced Genetic Analysis 27 ancestry types with population-specific disease risks with population-specific disease risks Cardiovascular genetics : APOE, PCSK9, LDLR, Factor V Leiden, MTHFR, CYP2C19 : APOE, PCSK9, LDLR, Factor V Leiden, MTHFR, CYP2C19 Neurological genetics : LRRK2, SNCA, GBA1, BDNF, COMT, SLC6A4 (Parkinson's, Alzheimer's, MS) : LRRK2, SNCA, GBA1, BDNF, COMT, SLC6A4 (Parkinson's, Alzheimer's, MS) Cancer susceptibility : BRCA1/2, TP53, MLH/MSH (Lynch), APC (FAP), PTEN (Cowden) : BRCA1/2, TP53, MLH/MSH (Lynch), APC (FAP), PTEN (Cowden) Respiratory genetics : CFTR (CF), SERPINA1 (AAT), ADRB2, IL4RA (asthma) : CFTR (CF), SERPINA1 (AAT), ADRB2, IL4RA (asthma) Athletic performance : ACTN3, ACE, PPARGC1A, COL5A1, AMPD1 : ACTN3, ACE, PPARGC1A, COL5A1, AMPD1 SNP-based phenotype prediction (eye color, metabolism, drug response) (eye color, metabolism, drug response) Mixed ancestry profiling with component analysis with component analysis Carrier screening for 50+ genetic conditions ๐ Comprehensive Pharmacogenomics Drug metabolism profiling (CYP1A2, CYP2C9, CYP2C19, ALDH2, etc.) (CYP1A2, CYP2C9, CYP2C19, ALDH2, ...
First seen: 2025-10-10 18:32
Last seen: 2025-10-10 18:32