AI Bests Virus Experts, Raising Biohazard Fears

Summary

A new study claims that AI models like ChatGPT and Claude now outperform PhD-level virologists in problem-solving in wet labs, where scientists analyze chemicals and biological material. This discovery is a double-edged sword, experts say. Ultra-smart AI models could help researchers prevent the spread of infectious diseases. But non-experts could also weaponize the models to create deadly bioweapons. The study, shared exclusively with TIME, was conducted by researchers at the Center for AI Safety, MIT’s Media Lab, the Brazilian university UFABC, and the pandemic prevention nonprofit SecureBio. The authors consulted virologists to create an extremely difficult practical test which measured the ability to troubleshoot complex lab procedures and protocols. While PhD-level virologists scored an average of 22.1% in their declared areas of expertise, OpenAI’s o3 reached 43.8% accuracy. Google's Gemini 2.5 Pro scored 37.6%. Seth Donoughe, a research scientist at SecureBio and a co-author of the paper, says that the results make him a “little nervous,” because for the first time in history, virtually anyone has access to a non-judgmental AI virology expert which might walk them through complex lab processes to create bioweapons. “Throughout history, there are a fair number of cases where someone attempted to make a bioweapon—and one of the major reasons why they didn’t succeed is because they didn’t have access to the right level of expertise,” he says. “So it seems worthwhile to be cautious about how these capabilities are being distributed.”Months ago, the paper’s authors sent the results to the major AI labs. In response, xAI published a risk management framework pledging its intention to implement virology safeguards for future versions of its AI model Grok. OpenAI told TIME that it "deployed new system-level mitigations for biological risks" for its new models released last week. Anthropic included model performance results on the paper in recent system cards, but did...